as much as possible, and that's good advice, but consider that the
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the biggest gain from & and ~ is that they let you mix and match regexes. instead of writing a single spaghetti monster regex that tries to do everything, you can break it down into smaller, simpler pieces and then combine them with boolean operators. this makes your regexes easier to read, write and maintain. this is best illustrated in the web app that came with the paper (https://ieviev.github.io/resharp-webapp/) where you can visually see how the different components of a regex are combined, and how they contribute to the final match.